The six modules
What is an LLM?
AI → ML → DL → LLM. The core trick in one sentence. Tokens and embeddings. Reasoning with meaning (why RAG works). Scale and emergent behaviour, why today's models can do things that failed last year.
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How is an LLM made?
Pre-training, supervised fine-tuning, RLHF, DPO. Domain-FT (Med-PaLM, MedGemma) versus RAG. The Transformer and attention. Context window, why you put your question at the bottom and what “lost in the middle” means for long ESC guidelines.
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The players, opportunities for the cardiologist
ChatGPT, Claude (and Anthropic's ethical positioning), Gemini and DeepSeek. Which for which task: letters, full guidelines, code, image, voice. Cardio choice matrix. The exponential pace and what it means for you.
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Cardio prompt architecture
The five building blocks (role/context/task/format/uncertainty). Provide source instead of asking source. Five live exercises: DDx for chest pain, discharge letter from dictation, patient leaflet B1, echo summary for MDT, teaching with case + learning questions.
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Risks, and how to frame them
Hallucinations as a feature, GDPR traffic light (green/amber/red), bias in the model and in yourself (automation bias), the four rules of thumb and local governance (DPIA, ESC AI Hub, EACVI). Final exercise: hallucination hunt.
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The big case, cardiogenic shock after anterior wall infarction
One realistic case adapted for teaching (Impella, VA-ECMO, LVAD screening) on which you apply everything: summarising in three formats, DD sparring, fact-checking, treatment plan vs. guideline, prompt iteration & privacy. Five work assignments, ten multiple-choice questions.
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